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盐酸氨溴索联合多巴胺治疗新生儿感染性肺炎疗效分析

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  [摘要] 目的 探讨盐酸氨溴索葡萄糖注射液联合小剂量多巴胺治疗新生儿感染性肺炎的临床效果。 方法 选择我院2014年9月~2015年2月收治的新生儿感染性肺炎患儿68例,随机分为对照组和观察组。对照组采用常规抗感染对症支持治疗,观察组在常规治疗的基础上加用盐酸氨溴索葡萄糖注射液及小剂量多巴胺治疗。比较两组的治疗效果、症状消失时间及治疗过程中不良反应发生情况。 结果 观察组总有效率(97.06%)显著高于对照组(70.59%),观察组的4种呼吸系统临床症状的消失时间均比对照组短,差异有统计学意义(P<0.05)。 结论 在常规抗感染对症支持治疗的同时,盐酸氨溴索葡萄糖注射液联用小剂量多巴胺治疗新生儿感染性肺炎临床效果好,值得推广。
中国论文网 /6/view-11754613.htm
  [关键词] 盐酸氨溴索;多巴胺;新生儿感染性肺炎;剂量
  [中图分类号] R722.13+5 [文献标识码] B [文章编号] 1673-9701(2015)20-0035-03
  An analysis of the curative efficacy of ambroxol hydrochloride combined with dopamine in the treatment of neonatal infections pneumonia
  JIA Lifang ZHAO Qian LI Riqing
  Department of Neonatology, Fenyang Hospital in Shanxi Province, Fenyang 032200, China
  [Abstract] Objective To discuss the clinical efficacy of ambroxol hydrochloride glucose injection combined with small dose of dopamine in the treatment of neonatal infections pneumonia. Methods All 68 children patients with neonatal infections pneumonia who were admitted to our hospital from September 2014 to February 2015 were selected. They were randomly assigned to the control group and the observation group. The control group was given regular symptomatic and supportive treatment of anti-injection, and the observation group was further given ambroxol hydrochloride glucose injection combined with small dose of dopamine on the basis of regular treatment. Curative efficacy, symptom disappearing time and the incidence of adverse effects during the treatment were compared between the two groups. Results The total effective rate (97.06%) in the observation group was significantly higher than that (70.59%) in the control group. The disappearing time of four kinds of clinical respiratory symptoms in the observation group was all shorter than that in the control group, and the difference was statistically significant between the two groups(P<0.05). Conclusion At the same time of regular symptomatic and supportive treatment of anti-injection, ambroxol hydrochloride glucose injection combined with small dose of dopamine in the treatment of neonatal infections pneumonia has a clinical efficacy, which is worthy of promotion.
  [Key words] Ambroxol hydrochloride; Dopamine; Neonatal infections pneumonia; Dose
  新生儿感染性肺炎是常见疾病,发病率位居新生儿感染性疾病之首,病情如未及时控制,可能导致发生心力衰竭、呼吸衰竭等并发症,是引起新生儿死亡的重要原因之一[1]。如何更快控制病情改善预后一直是新生儿科医师面临的问题。近年来,我科使用盐酸氨溴索葡萄糖注射液联合小剂量多巴胺辅助治疗新生儿感染性肺炎,效果显著,现报道如下。
  1 资料与方法
  1.1一般资料
  选取2014 年9 月~ 2015 年2 月我院NICU收治的新生儿感染性肺炎患儿共68例。诊断标准:①均符合《实用新生儿学》第4版[2]中关于新生儿感染性肺炎的临床表现及诊断标准:呼吸急促,常伴呻吟、憋气,呼吸暂停,体温不稳,黄疸等;②肺部听诊:可闻及干湿��音,③其他症状:部分患儿有发热、少尿、抽搐及肝脏肿大等;④X 线胸片检查:符合新生儿肺炎影像学表现[3]。将患者随机分为观察组、对照组,观察组34例,男23 例,女11 例,平均年龄(2.0±0.5)d,平均体重(3.28±0.36)kg;对照组34 例,男22 例,女12 例,平均年龄(2.0±0.3)d,平均体重为(3.32±0.27)kg。两组患儿一般资料(年龄、性别、病程、病情轻重、并发症等)比较差异无统计学意义(P>0.05)。

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